Derek Lowe’s writeup is good: https://www.science.org/content/blog-post/progress-against-p...

The founders of Lovable and Builder.ai individually received more funds than the whole group of the researchers behind this medicine...

• Retric

  today at 6:03 PM

  That’s talking about the ROI of a winning lottery ticket.

  As we can’t know ahead of time which medicine works you need to fund many teams at the beginning.

If you want to see what the side effects look like, look at ex Senator Ben Sasse: https://youtu.be/7CFo6-6BN9k?si=2B3dqB4rOhAnPiZl

Totally naive question: is this a situation where stacking the drug with chemo might be even better?

Paper: https://www.nejm.org/doi/full/10.1056/NEJMoa2605555?query=fe...

I hope they can get this to people quickly. Someone I love has been diagnosed with stage 3 end of Feb this year and it's utter hell. For everyone, not just the patient.

• thowland

  today at 5:26 PM

  While not fully approved, the company has early access available to people who meet the treatment criteria and would potentially benefit. Their HCP should evaluate this (it's not all types of pancreatic cancer, and it's not a silver bullet - but it looks like its double the survival time than current chemo). Hopefully this evolves into a new class of treatment.

Source article for those interested:

https://www.nejm.org/doi/full/10.1056/NEJMoa2505783

Paywalled but has a free access option if you make an account.

Always a money-generator.

Researchers need to find permanent cures.

• hackyhacky

  today at 6:00 PM

  Always baffling to me that people accuse researchers and doctors, people who have devoted their life to helping others, of brazen greed and deception. With no evidence, of course. Maybe the accusation says more about you than about them?